Background: The present clinical trial was designed to investigate the effectiveness of subgingivally delivered satranidazole (SZ) gel as an adjunct to scaling and root planing (SRP) in the treatment of smokers with chronic periodontitis. Methods: Sixty smoker subjects with probing depth (PD) ≥ 5 mm were selected. Thirty subjects each were randomly assigned to SRP + placebo and SRP + SZ. SZ or placebo (0.1 mL) was injected into the pocket using a syringe with a blunt cannula. The clinical outcomes evaluated were plaque index (PI), gingival index (GI), clinical attachment level (CAL) and PD at baseline, 1 month, 3 months and 6 months. Results: At 6 months, SRP + SZ resulted in greater mean reduction (3.05 mm) in PD as compared to SRP + placebo (1.97 mm; p < 0.05) and also a greater mean CAL gain (2.89 mm) in SRP + SZ as compared to SRP + placebo (1.88 mm; p < 0.05). Conclusion: When compared to the placebo, the adjunctive use of 3% SZ resulted in significant improvement in clinical outcome in the treatment of chronic periodontitis among smokers.
|Message from the President of the International Academy of Periodontology September 2013 Mark Bartold||Download|
|Comparison of Amnion Allograft with Connective Tissue Graft for Root Coverage Procedures: A Double-Blind, Randomized, Controlled Clinical Trial Amir Alireza Rasouli Ghahroudi, Afshin Khorsand, Amir Reza Rokn, Sepideh Seyedzadeh Sabounchi, Tadollah Soleimani Shayesteh and Ahmad Soolari||Download|
|Clinical and Radiographic Evaluation of Single-Tooth Dental Implants Placed in Grafted Extraction Sites: A One-Year Report Ahmad Kutkut, Sebastiano Andreana and Edward Monaco Jr.||Download|
|IAP World Conclave||Download|