Background: This preliminary study assesses the effects of initial periodontal treatment on salivary levels of 8-hydroxy-deoxyguanosine (8-OHdG) as a marker of oxidative stress in patients with chronic periodontitis (CP). Methods: At baseline, clinical parameters and saliva samples were obtained from 20 patients with CP and 10 patients with clinically healthy periodontium. Saliva samples were collected, and clinical periodontal measurements were repeated at 2, 4, and 8 weeks after initial periodontal therapy in patients with CP. An enzyme-linked immunosorbent assay was used to investigate 8-OHdG levels of saliva samples. Results: Statistically signifi cant higher 8-OHdG levels of saliva and a significant decrease after initial periodontal therapy were determined in the CP group (p < 0.001). A significant positive correlation was found between 8-OHdG levels of saliva and clinical periodontal measurements (p < 0.001) Conclusion: Within the limits of this short-term preliminary study it can be concluded that the estimation of 8-OHdG levels in saliva may be used to evaluate the oxidative stress in periodontitis patients. It also appears that oxidative stress, which is reflected by salivary 8-OHdG levels, might reflect the present status of periodontal health.
|Message from the President of the International Academy of Periodontology September 2013 Mark Bartold||Download|
|Comparison of Amnion Allograft with Connective Tissue Graft for Root Coverage Procedures: A Double-Blind, Randomized, Controlled Clinical Trial Amir Alireza Rasouli Ghahroudi, Afshin Khorsand, Amir Reza Rokn, Sepideh Seyedzadeh Sabounchi, Tadollah Soleimani Shayesteh and Ahmad Soolari||Download|
|Clinical and Radiographic Evaluation of Single-Tooth Dental Implants Placed in Grafted Extraction Sites: A One-Year Report Ahmad Kutkut, Sebastiano Andreana and Edward Monaco Jr.||Download|
|IAP World Conclave||Download|